| abstract |
The invention relates to a modified compound that has at least one other functional group, in particular a biomolecule or macromolecule, characterised by at least one x-fold (x≥1 ) chemoselectively incorporated phosphoramidate group of general formula (I), -NPO(OR 1 )(OR1'), and/or at least one x-fold (x≥1 ) chemoselectively incorporated phosphonamide group of general formula (Ia), -NPO(R 1 XOR 1' ), where R 1 and R 1' are selected from the group containing glycerol, polyglycerol, PEG polymers of general summation formula C 2n H 4n+2 O n+1 where n ≥ 1, Cn alkyI chains where n ≥ 1; functionalised Cn alkyI chains where n ≥ 1, aryls, heteroaryl, siIyI, lipids, fluorophores, saccharides, peptides, crown ethers, or a linker that links the aforementioned groups, and where R 1 and R 1' can be identical or different to/from one another. |