| abstract |
The invention relates to the use of (1 S ,3 R ,7S,8 S ,8a R )-1,2,3,7,8,8a- hexahydro-3,7-dimethyl-8-[2-[(2 R ,4 R )-tetrahydro-4-hydroxy-6-oxo-2 H -pyran-2-yl]ethyl-1-naphthalenyl propanoate derivatives, optionally mono- or di-methylated at the carbon in the alpha position of the propanoic acid, having formula (I), in which: R is CH 3 CH 2 CO-, (CH 3 ) 2 CHCO- or ( C H 3 ) 3 CCO-, the hydroxyacid forms thereof and the pharmaceutically acceptable salts of said hydroxyacids, as neuroprotective compounds suitable for use in the prevention and/or treatment of neurodegenerative diseases or diseases associated with unwanted oxidation or pathological processes associated with age, or epilepsy, epileptic seizures or convulsions. |