http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010099204-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4847cb2653103c33123bed377d452723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef12ca66f38eab319fe3136d6fbfd22f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e51bb062c7f7ae2a31ed2f4bc3b36aab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_777ef660ac2480cfefb8320d172ef4ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26646f4754b2ebb7fb6d0dced6aeec5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_872bc04989061426c7f73c1d206918d3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2010-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_024fce18eb231ed0c74486919193b534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d15e29d41f2b47780aae003d374fa9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54fcdb0203c946b71e01b16243324a18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a791a45d7be0b6f4f6cf1ca0b4867e06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c36e103f15d6c0cc3c5e79e65ba7460 |
publicationDate | 2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2010099204-A2 |
titleOfInvention | Secreted fxyd proteins expressed in response to epithelial tissue damage, and uses therefor |
abstract | Secreted FXYD family proteins are expressed by intestinal mucosa and/or associated tissues to regulate cell production in intestinal crypts in response to tissue damage. Such tissue damage may arise from disease, exposure to injurious chemicals (e.g., due to poisoning, chemotherapy, chemical weapons), or exposure to injurious radiation (e.g., due to nuclear power accidents, radiological weapons, radiation therapy). Because these proteins are secreted in response to epithelial tissue damage, some of them are implicated in tissue repair response or an inflammatory response which prolongs or exacerbates the tissue damage. Examples of these proteins include FXYD 3, FXYD 4, and FXYD 5. Diagnostic methods based upon the role of the FXYD proteins in epithelial tissue damage are disclosed. Also provided are antibodies raised against the FXYD family proteins, a kit for detecting at least an epitope of a polypeptide, a method of producing an antibody raised against an epitope of a polypeptide, and a method of diagnosing damage to an epithelial tissue. |
priorityDate | 2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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