| abstract |
The invention relates to a modified-release oral pharmaceutical composition in capsules with microspheres, containing loratadine, phenylephrine and pharmaceutically acceptable excipients. Said composition has immediate bioavailability, with plasmatic concentration values within the therapeutic window with a uniform, continuous release. The invention also relates to a method for the production of the composition and to the use thereof for treatment as a nasal decongestant and an antihistamine. |