Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_835b9a2a5f608ac527ff3b8df007bbbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9fa07f5b631bb39ecd22144f25e42ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_914a708b46c9769031c8c5bcb91afc4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0c00f40f594402e7eefd267cf9bd2f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f561a34a98c9da7cdd222fa87a8b9bc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9c739f379667581167727eb91a2cf4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c58602a1d949b3f58d73dbe87688065e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f6618ffa97d621cdfe9437fd02fcb7a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B90-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B34-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-416 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-1455 |
filingDate |
2009-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2cf7344eaedb4b496cb6a956d93a106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba2ecd84d017c23bc4120608e35d16c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ffd89b5ac87eeeb9982903b54199968 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7047ca06cee169a8f4724c8869b1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3ca6d4f9cf08d4f8639aef1208e0dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e54231eb866ab8d1fd7eecf40683ef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2c39d3a556f0bd71ef2245d2c046ef |
publicationDate |
2010-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010090673-A1 |
titleOfInvention |
Method and apparatus for depth-resolved fluorescence, chromophore, and oximetry imaging for lesion identification during surgery |
abstract |
A tomographic fluorescent imaging device for imaging fluorophores in biological tissues has a scanned laser for scanning the tissue and a camera for receiving light from the biological tissue at an angle to the beam at a second wavelength ten or more nanometers greater in wavelength than the wavelength of the laser. Use of both intrinsic and extrinsic fluorophores is described. Images are obtained at each of several positions of the beam. An image processing system receives the series of images, models a path of the beam through the tissue, and determines depth of fluorophore in tissue from intersections of the modeled path of the beam and the path of the received light. The laser is of 600 nm or longer wavelength, to provide penetration of tissue. The imaging device is used during surgery to visualize lesions of various types to ensure complete removal of malignant tumors. An alternative embodiment uses differences in intensity of fluorescent radiation from tissue as observed at different wavelengths to determine depth of fluorophore in tissue. An embodiment operates at multiple wavelengths to construct tomographic images of chromophores, such as hemoglobin, and is capable of dynamic imaging. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105434046-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I577331-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023076899-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10568535-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11564639-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022082931-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129562-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11510600-B2 |
priorityDate |
2009-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |