| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77c2f907d13534169a46ac8441351f38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c1ea4d4b03579953e9a66e331ae7514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_646acd82cfe6e936cb3079d5ea0a6c22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N45-00 |
| filingDate |
2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a66981912010a015411334f23079025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a339b2f9aaa03ffe55becfc3f727af7 |
| publicationDate |
2010-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010088286-A1 |
| titleOfInvention |
Synthetic conjugates and uses thereof |
| abstract |
The present disclosure provides a cross-linked material comprising conjugates which include two or more separate affinity ligands bound to a non-polymeric framework, wherein the molecular weight of the non-polymeric framework is less than 10,000 Da; and multivalent cross-linking agents that non-covalently bind the affinity ligands of the conjugates and thereby cross-link the conjugates to form a cross-linked material, wherein the non-covalent bonds between the multivalent cross-linking agents and the affinity ligands are competitively dissociated in the presence of excess amounts of a target molecule. The present disclosure also provides methods of making and methods of using these materials. In other aspects, the present disclosure provides exemplary conjugates including conjugates for use in glucose responsive cross-linked materials. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014088836-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9427475-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2598170-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9884125-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9889205-B2 |
| priorityDate |
2009-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |