abstract |
In the invention, a film-shaped base in which one or more types of sugars and sugar alcohols are dispersed as fine particles is prepared by dispersing water and an edible polymer soluble in an organic solvent having a dissolution parameter of 9.7 or more and one or more types of particles having a particle diameter of from 0.1 to 60 µm selected from the group consisting of sugars of mono- to tetrasaccharides which are not dissolved in an organic solvent and sugar alcohols thereof in the organic solvent, and a film-shaped preparation is prepared by further incorporating a drug in the film-shaped base. As a result, intraoral film-shaped base and preparation having a rapid dissolution profile in the mouth and sufficient film strength, and further having a reduced sticky feel due to a water-soluble polymer in the mouth and an improved tactile sense when touched by the fingers can be provided. |