http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010083532-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ec5ec77cfe3b5cfc3ecdaf46aa2a19e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf9697b4ed2dfb565cce24b904cf63f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f036cf71fa4d9e4f91265c1751405be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb42082cfece50b2aada523da54207a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2010-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_133714ebfc628247ce70d7cf14457472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7d2a93ded923e839b65a016d4941972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f435d52a67dcb61e4452dacaaf74256 |
publicationDate | 2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2010083532-A1 |
titleOfInvention | Fatty acid binding proteins as drug targets for modulation of endocannabinoids |
abstract | The invention provides a method of modulating the level of an endocannabinoid in a subject in need thereof comprising administering an effective amount of an agent that inhibits the interaction of the endocannabinoid with an intracellular fatty acid binding protein (FABP). The invention also provides a method of identifying an agent for modulating the level of an endocannabinoid in a subject comprising testing the agent for its ability to modulate binding of the endocannabinoid with an intracellular FABP. The invention also provides a method of identifying an agent for modulating the level of an endocannabinoid in a subject comprising testing the agent for its ability to modulate expression of an intracellular FABP. The invention also provides a method of identifying an agent for treatment of a neurological disorder comprising testing the agent for its ability to modulate the interaction of an endocannabinoid with an intracellular FABP. The invention also relates to modulation of levels of fatty acid amides for treatment or amelioration of diseases or disorders by modulating binding of the fatty acid amides to fatty acid binding proteins. In one embodiment, the fatty acid binding protein is one or more of FABP3, FABP5, and FABP7. In one embodiment, the level of an endocannabinoid is modulated. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10466232-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016149426-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017156354-A1 |
priorityDate | 2009-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 199.