abstract |
The present invention relates to novel acid addition salt of Sibutramine, [1-(4- chlorophenyl)-N,N-dimethyl-a-(2-methylpropyl)-cyclobutane-ethanamine] Sibutramine Maleate and the processes for their preparation.The present invention further relates to novel polymorphic forms of Sibutramine Fumarate, which include an anhydrate (Form-I), dihydrate (Form-II) and an amorphousform. |