http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010074480-A3

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filingDate 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57dfddeab708b80f00b8ca37c4163fa9
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publicationDate 2010-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010074480-A3
titleOfInvention Novel pyrazolodiazepine compounds as a transglutaminase inhibitor, the preparation method thereof and a composition containing the same
abstract The present invention relates to the novel pyrazolodiazepine compounds which potently inhibit the activity of transglutaminase in a dose dependent manner. Accordingly, it has been confirmed that the inventive compounds show potent inhibiting effect on the hyper- activated transglutaminase when the transglutaminase is over-expressed. Therefore the compounds can be useful in treating or preventing the disease caused by increased activation of transglutaminase.
priorityDate 2008-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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