| abstract |
Disclosed are a prophylactic or therapeutic agent for diabetes or obesity and a pancreas-protective agent, each of which can exhibit a high therapeutic efficacy and has few adverse side effects. Specifically disclosed is a pharmaceutical preparation for preventing or treating diabetes or obesity, which comprises a combination of (1) a DPP-IV inhibitor, (2) a GPR119 agonist and (3) a biguanide or an a-glucosidase inhibitor. Also specifically disclosed is a pancreas-protective agent comprising a combination of (1) a DPP-IV inhibitor, (2) a GPR119 agonist and (3) a biguanide or an a-glucosidase inhibitor. |