| abstract |
The invention relates to peptides, such as can be isolated from camel milk, and can be used as an active substance in pharmaceutical composition, in particular for use in case of medical indications that can be treated by means of inhibiting human DPP4, CD26, zAAP, and/or DPP8 and/or DPP9, in particular diabetes mellitus type 2, obesity, and/or cardiovascular diseases, and diseases that are caused by T-cells, or that can be treated by affecting T-cells, and in particular by inhibiting DPP4 or the cell-bonded form thereof CD26 and/or APN and/or zAAP, such as autoimmune diseases. The invention further relates to pharmaceutical compositions for use in case of neuronal diseases that can be treated by inhibiting DPP4 or CD26 and/or inhibiting APN and/or zAAP and/or in case of neuronal diseases that can be treated by inhibiting DPP 8 and/or DPP9. |