| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15ceddf7c375bcbc6dca5ff0649ea58d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fbb2a22f25e9bd7a953317ac20a7b2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ffdd0403966b3257cdff37810d77910 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd2ed1b7c6b4a7abe7f55dd2191d0768
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29072ecbcd1599d4ee72dd236e9d9912 |
| publicationDate |
2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010068758-A1 |
| titleOfInvention |
Somatic cell-derived pluripotent cells and methods of use therefor |
| abstract |
Provided are methods for producing a reprogrammed fibroblast. The methods can include growing a plurality of fibroblasts in monolayer culture to confluency; and disrupting the monolayer culture to place at least a fraction of the plurality of fibroblasts into suspension culture under conditions sufficient to form one or more embryoid body-like spheres, wherein the one or more embryoid body-like spheres comprise one or more reprogrammed fibroblasts that express one or more markers not expressed by a fibroblast growing in the monolayer culture prior to the disrupting step. Also provided are reprogrammed fibroblasts produced by the disclosed methods, formulations that include reprogrammed fibroblasts, and methods for treating an injury to a tissue in a subject by administering to a subject in need thereof a composition of reprogrammed fibroblast cells in a pharmaceutically acceptable carrier. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012071108-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730975-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102224273-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104087551-A |
| priorityDate |
2008-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |