Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19e6c64a144e8c32fbe313482775232f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8567851efcf1120ecb9c5bb5dec06ad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11639a085e16611d2898064a597b9948 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
filingDate |
2009-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7350370cdae0974139057670cdae4ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a89c7b18cd28de8b25d60bc77d156a5 |
publicationDate |
2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010067755-A1 |
titleOfInvention |
Therapeutic agent for hypertension, method for treating hypertension, method for diagnosing hypertension, and method for screening therapeutic agent for hypertension |
abstract |
Disclosed are a therapeutic agent for hypertension and others, which can be developed by studying a gene that is involved in circadian rhythm and causes hypertension. The therapeutic agent for hypertension comprises, as an active ingredient, the following specific substance: the specific substance can affect the expression of at least one gene selected from a first gene which is involved in the circadian rhythm in the adrenal cortex, a second gene which is affected by the behavior of the first gene and is involved in the production of adrenal cortex hormone, and a third gene which is involved in the signaling between the first gene and the second gene, or the specific substance can affect the activity of a product of the gene. It is confirmed that a blood pressure changes when the specific substance is administered. The therapeutic agent for hypertension can be screened utilizing a specific cell which contains the first gene, the second gene or the third gene. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015521863-A |
priorityDate |
2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |