| abstract |
Compounds of the formula (I) including any possible stereoisomers thereof, wherein: R 1 is hydrogen or halo; R 4 is a monophosphate, diphosphate or triphosphate ester; or R 4 is a group of formula (II) R 7 is optionally substituted phenyl; naphthyl; indolyl or N -C 1 -C 6 alkyloxycarbonyl- indolyl; R 8 is hydrogen, C 1 -C 6 alkyl, benzyl; R 8' is hydrogen, C 1 -C 6 alkyl, benzyl; or R 8 and R 8' together with the carbon atom to which they are attached form C 3 -C 7 cycloalkyl; R 9 is C 1 -C 10 alkyl, benzyl, or optionally substituted phenyl; or a pharmaceutically acceptable salt or solvate thereof. pharmaceutical formulations and the use of compounds I as HCV inhibitors. |