| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_305216efec6a434fd525d77fa9e19e33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62924da566ff64c0088b4cdc3af46923
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75e24281e85885ab3c3d1a4343daedbf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-51 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16ef51455da83dd82ee134c90cea2108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1dd5a2611c5e9e7fa5e57f05bd9227 |
| publicationDate |
2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010059829-A2 |
| titleOfInvention |
Compositions and methods for triggered release rna therapeutics |
| abstract |
Provided are compositions for delivery of an active agent including a ribonucleic acid, an RNAi-inducing agent, or an antisense agent, comprising a DILA2 amino acid compound and an intracellularly-cleavable peptide of from six to 100 amino acid residues in length, the intracellularly-cleavable peptide comprising two or more nucleic acid-binding region amino acid sequences connected by one or more intracellularly-cleavable linker amino acid sequences, wherein the nucleic acid-binding regions each contain two or more positively-charged amino acid residues. Further provided are methods of using the compositions to efficiently deliver an active agent such as a nucleic acid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023156413-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018106418-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103172701-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103172701-A |
| priorityDate |
2008-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |