Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af24ab34d37898a997acd53f56b8edd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0cb2379e3aa8e570411770547ee8e39a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09dee7550a7d757780ff06a9db207a71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a521cfa321c963978df8ae98a84056a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3a18c22315bb463b01094b8cfed2930 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2648 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-28 |
filingDate |
2009-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac5b8e3a577f0b2573e030b6257bc562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7fc0a8d4386970064d7468b51c99cb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d838196b0deb21f9be810d9d3a6d5919 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_273c3ec89c69a2961e2100e67e725ef5 |
publicationDate |
2010-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010055866-A1 |
titleOfInvention |
Polyalkylene glycol derivative and method for producing same |
abstract |
A method for producing a polyalkylene glycol derivative which has a molecular weight and purity high enough to be used in pharmaceutical applications. Specifically disclosed is a method for producing a polyalkylene glycol derivative represented by formula (X) R-(OA) n OH by steps (A), (B), (C),(D) and (E). Step (A): An alkali catalyst is added to a compound represented by formula (Y) R-OH in an amount of 5-50% by mole. Step (B): A polyalkylene glycol derivative is obtained by reacting an alkylene oxide having 2-4 carbon atoms at a temperature of 50-130˚C until the average mole number of added oxyalkylene groups (OA) reaches the range of 5-500. Step (C): The derivative of step (B) is diluted by adding 10-5,000% by mass of a hydrocarbon solvent, and the remaining water content is removed by azeotropy. Step (D): The derivative of step (B) is reacted with an alkylene oxide having 2-4 carbon atoms at a temperature of 50-130˚C until the average mole number of added oxyalkylene groups (OA) (n) reaches the range of 600-2,000. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2896642-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015134862-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018521832-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9284408-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020138308-A1 |
priorityDate |
2008-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |