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publicationDate 2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010050902-A1
titleOfInvention Vaccines, which combine the antigen and toll-like receptors
abstract Invention represents new vaccine that contains DNA/nucleic acid coding for fusion protein between the antigen and at least Toll like receptor (TLR). The fusion protein optionally contains signalling peptide and dimerization domain that together with an active/activated intracellular domain of TLR triggers signalling of innate and adaptive immune response to antigen of the fusion protein. The invention refers to vaccine for preparation of vaccine composition for treatment and/or prevention of diseases and/or disorders that can be identified by the self antigens; for preparation of vaccines for production of antigens to be applied for passive immunization or in diagnostic testing. The invention refers to the host organism, preferentially an animal that was exposed to vaccination with the vaccine according to the invention.
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