Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1a3a291c372a6fed6d923d3c3ae9273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_478a25ee71d275aad349ae7b4dd1c248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c890d2f46f4e70e13173ceeba4d9bb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6e6429eb0a34dc1feec1bb65ef68846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35a08bb718da0b231f9f5d570466c0ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c47e2c6a556b797a7cc7fe66807b7ecb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bb6d7660cf31be26bf934a2ee76f67e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d843fb14b022b85cd09eb614684a1a85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7a3fbb7c8a862e5cb5457b3ca49cd31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc6484fa8b25e72749bce3e8256b62a9 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6506 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 |
filingDate |
2009-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3baf45abe6a9b5b8fcd5c88b376c700f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_804c8a6e2858ff4bf1b8d7213296fdad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48c7f48baeef475162b3447c0ef5ffc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48abe63ab3f12daf91c5acfa7b79ca01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6caa357b95c20037bae998be7ffe98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_211848d35c12e1d9822d572b38e5856d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f024e12761b6787b74edaf0c7da371e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49f46bf7bf456569a3e04faefe2ca5c3 |
publicationDate |
2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010050830-A1 |
titleOfInvention |
Process for the preparation of [1-hydroxy-2-(1h-imidazol-1-yl)- ethylidene]bisphosphonic acid |
abstract |
A process for the preparation of [1-hydroxy-2-(1H-imidazol-1-yl)- ethylidene]bisphosphonic acid consists of the reaction of aqueous solution of 1Η-imidazole-1-acetic acid hydrochloride with phosphorus trichloride followed by removal of the excess of phosphorus trichloride, addition of water and hydrolysis of the reaction products. In order to isolate the product the post-reaction mixture is filtered and the anti-solvent is added to the aqueous filtrate in order to crystallize out [1-hydroxy-2-(1H-imidazol-1-yl)-ethylidene]bisphosphonic acid monohydrate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011023280-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106699809-A |
priorityDate |
2008-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |