abstract |
Glycosyl-derivatives of puerarin presented by formula (I) or pharmaceutically acceptable salts thereof, wherein R is monosaccharides (6-carbon saccharides or 5-carbon saccharides) or oligosaccharyl (2-5 glycosyl selected from 6-carbon saccharides or 5-carbon saccharides); the pharmaceutically acceptable salts is inorganic or organic base addition salts. The glycosyl-derivatives of puerarin in the present invention or pharmaceutically acceptable salts thereof maintain higher stability and solubility, improve bioavailability and enhance therapeutic effect compared with puerarin. |