| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0c0ecea6d2ea4c9881951021c08623e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_057034ba4aac13af53b2ca4415ff20e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_106e919b9a4b07986a744ce58337df72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0e564374fedf34b36103d36e6455a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate |
2009-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_068deff51e3c36fe6c7a49fe1b155f89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68e236ddb02bf0cafde49da39b4a308c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e1ef23bc961ce77c26039dddde1821b |
| publicationDate |
2010-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010043701-A1 |
| titleOfInvention |
Clarification process |
| abstract |
The present invention relates to a method for the clarification of a cell broth containing cells by the following steps: contacting the cell broth with a particulate anion exchange material having a specific density of the particles of between 1.4 and 3, allowing an adequate incubation time, and separating the resulting cell pellet from the supernatant layer. The present invention further relates to a method for the recovery of secreted desired biological substances from a cell broth containing cells producing the secreted desired biological substance by contacting the cell broth with particulate anion exchange material having a specific density of the particles of between 1.4 and 3 g/ml, allowing an adequate incubation time to result in formation of a cell pellet and a supernatant layer, separating the resulting cell pellet from the supernatant layer and extracting the secreted desired biological substance from the supernatant layer. Optionally, residual biological substance can be further extracted from the resulting cell pellet by one or more washing step. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012030512-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10695744-B2 |
| priorityDate |
2008-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |