| abstract |
The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R 1 represents a C1 -C3 alkyl group; R 2 represents a hydroxy -C1 -C4 alkyl group and the like; R 3 represents a halogeno group, a halogeno-C1 -C3 alkyl group and the like; R 4 represents a hydrogen atom, a halogeno group and the like,- R 5 represents a sulfamoyl group or a C1-C3 alkylsulf onyl group; R 6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing. |