http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010041837-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57d51dbe7a6a8c2f0870d4c8e4401621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4f4b236283d8d8645f10aec1a7352fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9789480ef0bf49d5be234e262d4d6af6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-484 |
filingDate | 2009-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4d767b78550e7c19f4cd88f71df4ef0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03d59d7b484087642c4124411eb8bace http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ace804adb74deabbbeff24fa400b793 |
publicationDate | 2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2010041837-A2 |
titleOfInvention | A use of the liquiritigenin abundant extract or liquiritigenin derived therefrom for increasing bile flow, choleretic effect, and for preventing and treating cholestatic liver diseases |
abstract | The present invention is related to a composition comprising an extract of licorice or liquiritigenin derived therefrom, which significantly increases bile flow rate and biliary excretion of bile acid, GSH and bilirubin. Consistent with these results, the inventive composition comprising an extract of licorice or liquiritigenin derived therefrom decrease the blood chemical markers including ALT as a hepatoprotective marker, and ALP and ?-GTP, as cholestatasis markers, and histochemical markers including central necrosis and inflammation in galactosamine/lipopolysaccharide-induced hepato-toxicity animal model when the inventive extract or compound of the present invention was orally and intravenously administrated thereto. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012062261-A |
priorityDate | 2008-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 271.