http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010040992-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f057d996ac15f8985fb8b0207a81ad07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f27884daec90a5efd3761dce84b1fb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47de0e7d8b65d0cf3c7683a1ca799e42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a42e8f1e8756e50138751c9644ca47e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2009-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e40c3433529e6418154cc64100ff24a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f97d7be888c02bb7fe30129dc1b4781b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d02c1d142519e6d8bb1c33d6566d166a |
| publicationDate | 2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010040992-A1 |
| titleOfInvention | Quinoline derivatives having dp and / or crth2 receptor activity |
| abstract | A compound of formula (I) for medicinal use: R 1 , R 2 , R 3 , R 4 and R 5 independently represent hydrogen, halogen, -S(O) n R 6 , -S(O) 2 NR 7 R 8 , -NR 7 S(O) 2 R 6 -NR 7 R 8 , -NR 7 COR 6 , -CONR 7 R 8 , -COR 6 , - NO 2 , -CN, -OR 7 , C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl, the latter two groups being optionally substituted by one or more fluoro atoms; R 6 is C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl, optionally substituted by one or more fluoro atoms; R 7 and R 8 independently represent hydrogen, C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl, the latter two groups being optionally substituted by one or more fluoro atoms; A is -O-, -S(O) n , -CR 9 R 10 , -NR 11 or -C(O); R 9 and R 10 independently represent a hydrogen, fluoro or C 1 -C 6 alkyl; R 11 and R 12 independently represent hydrogen or C 1 -C 6 alkyl; B is -C(R 9 R 10 )C(R 9 R 10 )- or C(R 11 )=C(R 12 ); and when A is -CR 9 R 10 , B may additionally be -OCR 9 R 10 , -NR 11 CR 9 R 10 or -S(O) n CR 9 R 10 ; W is C 1 -C 6 alkyl optionally substituted by one or more substituents independently selected from fluoro, aryl, heteroaryl or C 3 -C 7 cycloalkyl, the latter group being optionally substituted with one or more fluoro atoms; and X is a carboxylic acid group, a tetrazolyl group, or a group of formula -CONHS(O) 2 R 13 or -S(O) 2 NHCOR 13 ; R 13 is aryl, heteroaryl, C 1 -C 6 alkyl or C 3 -C 7 cycloalkyl, the latter two groups being optionally substituted by one or more fluoro atoms; and n is 0, 1 or 2. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9376393-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9199938-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013103317-A1 |
| priorityDate | 2008-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.