| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad604075123ae0218d3bbef1a565c969
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_811f613e4bff48093b01cb6d941b3176
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate |
2009-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ad4466a2267b507d2eda496386c4bec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d383e492df5c77d3f4dd1c04ca5f047a |
| publicationDate |
2010-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010034863-A1 |
| titleOfInvention |
Use of kinase inhibitors for the preparation of pharmaceutical compositions for treatment of parkinson’s disease, pharmaceutical compositions and diagnostic procedure for parkinson’s disease |
| abstract |
The present invention describes the direct relationship between the phosphorylation of the parkin protein and the formation of intracellular aggregates in neurons. Consequently inhibitors of casein kinase I and Cdk5 can be useful pharmaceutical compounds for the treatment of diseases associated with Lewy bodies, such as Parkinson’s disease and dementia with Lewy bodies. Furthermore, the identification of phosphorylated parkin in biological samples from the central nervous system, preferentially from an extracranial autonomic plexus, is a useful tool for diagnosis, including early diagnosis, of the aforementioned diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111410693-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021179952-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111410693-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111228266-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111228266-A |
| priorityDate |
2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |