http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010034041-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19538b4ae3d63def32521ff377a29a07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc14a3a08feee487e6cbab7686013853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e97f72287ac8d8a8876dd7d08e0b7cb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97fa404664166943121b2b8f12be5e4f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-75 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 |
| filingDate | 2009-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f2e470754d2ce88062edba5490a0ede http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c5988f59ae4359ebadc4a3ba69ae319 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d6d8005655db9c6f76f15ca1a8754e0 |
| publicationDate | 2010-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010034041-A1 |
| titleOfInvention | Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition |
| abstract | Peptides, peptidomimetics and derivatives thereof of the following general formula (I): H 2 N-GHRPX 1 X 2 X 3 -β-X 4 X 5 X 6 X 7 X 8 X 9 X 10 -X 11 , in which X 1 - X 10 denote one of the 20 g genetically coded amino acids, wherein X 8 , X 9 and X 10 individually or jointly may also denote a single chemical bond; X 11 denotes OR 1 in which R 1 equals hydrogen or (C 1 — C 10 ) alkyl, NR 2 R 3 with R 2 and R 3 are equal or different and denote hydrogen, (C 1 — C 10 ) alkyl or a residue -W-PEG 5-60K , in which the PEG residue is atteched via a suitable spacer W to the N-atom, or a residue NH-Y-Z-PEG 5-60 K, in which Y denotes a single chemical bond or a genetically coded amino acids from the group S, C, K or R and in which Z denotes a spacer, via which a polyethylene glycol (PEG)-residue can be attached, as well as their physiologically acceptable salts, and in which additionally β denotes an amino acid, whether genetically coded or not, or a peptidomimetic element, which have the additional property of inducing a bend or turn in the peptide backbone. Such amino acids include without limitation L-proline, D-proline, L-hydroxyproline, D-hydroxyproline, L-(O-benzyl)-hydroxyproline, D-(O-benzyl)-hydroxyproline, L-(O-tert, butyl)-hydroxyproline, 4-(O-2-naphtyl)-hydroxyproline, 4-(O-2-naphtyl-methyl)-hydroxyproline, 4-(O-phenyl)-hydroxyproline, 4-(4-phenyl-benzyl)-proline, cis-3-phenyl-proline, cis-4-phenyl-proline, trans-4-phenyl-proline, cis-5-phenyl-proline, trans-5-phenyl-proline, 4-benzyl-proline, 4-bromobenzyl-proline, 4-cyclohexyl-proline, 4-fluor-proline, L-tetrahydroisoquinoline-2-carboxyric acid (L-Tic), all diastereomers of octahydro-indole-2-carboxylic acid (Oic), and all diastereomers of 1-aza-bicyclo[3,3,0]octane-2-carboxylic acid or a residue selected from a group of peptidomimetic residues. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010043972-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010043444-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010043972-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010043444-A2 |
| priorityDate | 2008-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 365.