http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010032113-A3

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filingDate 2009-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df3157804542eb9f3f650b123f7a1fbc
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publicationDate 2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010032113-A3
titleOfInvention Composition and use of a long-acting oral bioadhesive endoparasiticide gel based on doramectin
abstract The present invention relates to the composition of an oral bioadhesive endoparasiticide gel based on doramectin, having a high degree of adhesion to equine oral mucosa and having a sweet flavour greatly facilitating the dosing thereof, procedures for the preparation and the utilisation thereof. Gastrointestinal helminthosis is a parasitic condition caused by nematodes of diverse families occasioning serious gastrointestinal disorders in equine livestock. Control of this illness is of great importance and advantageously achievable through the employment of appropriate antihelminthic agents such as doramectin, being a chemical compound widely administered by parenteral route and infrequently by oral route in liquid form due to the organoleptic and physicochemical characteristics of the compositions known up to the present. The present invention demonstrates that it is possible to administer doramectin in the pharmaceutical form of an oral gel at concentrations of up to 5.0% weight/volume, overcoming the organoleptic and physicochemical restrictions of the compositions known up to the present. Factors never heretofore included in oral endoparasiticide compositions based on doramectin, presenting a wide differential advantage compared with the compositions known up to the present. These and other characteristics, objectives and advantages of the present invention will be appreciated by those skilled in the art from the detailed description provided below in the present document, together with the attached claims.
priorityDate 2008-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 32.