http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010028443-A1

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filingDate 2009-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d64407978b5d0579865084c041a39a45
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publicationDate 2010-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010028443-A1
titleOfInvention Microrna target identification assay
abstract The invention relates to assays and kits for detecting microRNA (miRNA) targets through determining changes in length of poly(A) tails of messenger (mRNA). In particular, microRNA (miRNA) targets can be detected by treating a cell with a miRNA, or treating a cell to inactivate a miRNA produced by the cell, or treating a cell to prevent a miRNA from being produced by the cell; detecting poly(A) tail lengths of messenger (mRNA) molecules of the treated cell; detecting poly(A) tail lengths of mRNA molecules of a corresponding untreated cell; comparing poly(A) tail lengths on mRNA molecules between the treated cell and untreated cell; and detecting a target of the miRNA from changes in poly(A) tail lengths of mRNA molecules in a treated cell compared with an untreated cell.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011138787-A1
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