Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdd8cd8eb5adfc56cbfbbbb0936e3943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75f4c74972c2477c3edef0f73216c1a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f3db0d8c13bafdeb7c671ce61660e36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59f6260a93fe7f0aee93d2cbbf27b93d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a129cde39c83aa3792d57f690f82bf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a3ace35986e8e8a76ae0f2e7e21269c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c61d7a061ab76276f25d0e2c81eed9 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
filingDate |
2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d1127a4a0dd224519398fa45740f06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f58fdc0e6b3c77cd013452310d86f88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53681112b3e7950a6830a5f7b8bf9701 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_487b0e30991ff520025311d49e2f2809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e453a0c446035153dee246040c24e20b |
publicationDate |
2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010028089-A2 |
titleOfInvention |
Agents and methods for treatment of pain |
abstract |
The invention provides agents useful for treating pain. An exemplary agent comprises or consists of the a portion of a retroviral Tat protein. One such agent is the peptide Tat-NR2B9c. This peptide has previously been described as an agent for inhibiting damaging effects of stroke and similar conditions via inhibition of PSD95 interactions with NMDA receptors and/or NOS. The present application provides data showing that the Tat- NR2B9c peptides is effective in alleviation of pain. The alleviation of pain can be obtained at a dose of the peptide below the dose required to inhibit PSD-95 interactions with NMDAR or NOS. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10107796-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083776-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10995125-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015164378-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013543378-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463714-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10613079-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108079279-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10048275-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10414808-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541098-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019134150-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3693001-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015518836-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9594075-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3524257-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019107017-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975129-B2 |
priorityDate |
2008-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |