| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98d35cd90eac22fb869a062fb773f987
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14e883f563d3f87fc8e021410822af1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d466be25a7bcade71087d1364c441de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f09838134ece4952e4cb4bafc23126a3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2009-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3275a1ef555ac5ad7de3cc8dc1b23376
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40aa8bbff020857e4f2216ac807c4e3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f96b4f3fe5b04907a6d0e7bf9ca2aced |
| publicationDate |
2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010025952-A1 |
| titleOfInvention |
Method for genotyping ugt1a1*28 promoter region variant and systems useful therefor |
| abstract |
In a first aspect, the present invention relates to a method for genotyping an individual for (TA) 7 variants of the UGT1A1 promoter region. In particular, the present invention relates to a specific method using the PCR TaqMan system for genotyping individuals for the presence of the (TA) 6 or (TA) 7 UGT1A1 genotype. In a further aspect, the present invention relates to a kit allowing genotyping of an individual for variants of the UGT1A1 promoter region as well as systems for genotyping the same. Said kits and systems are particularly useful for the stratification of individuals undergoing drug therapy or being exposed to environmental occupational poison. In another embodiment, said methods, systems and kits are useful for prediction of safety, toxicity and/or efficacy of a substance, in particular, of a drug or product in a drug therapy or of substances intended to be used as active ingredients in pharmaceutical or non- pharmaceutical applications. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018235937-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11384385-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110997945-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3643791-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107043808-A |
| priorityDate |
2008-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |