Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e294ab01f917c861f6771e6c70a5b86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62e28d71e053b428234b0ecb133092ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91cb37aa4d155d030a3b6faa4bd1c877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_735c0c1be7d5c85b01652008324fe0d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdc3e95f71f2bd5b3ec20258fe47b6c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7544ddca2535a5d0e4ba1a92531434b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14143 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 |
filingDate |
2008-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ec0807998352434cb51f91d825ebc01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe39359aeaeff10b48c03c8d82cf073e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_285b9bd1c50f074594dcfd995ff77a28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4accdda71abc8eb9c7d5057f3cd6644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3b9f31c3457c628cab4c52a1be1438e |
publicationDate |
2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010025764-A1 |
titleOfInvention |
Insect-derived promoters for foreign proteins expression in insect cells |
abstract |
Insect-derived promoters for foreign proteins expression in insect cells. Regulatory polynucleotide sequences which drive the expression of major insect proteins (hexamerins) at specific evolution stages of larva have been isolated from insects ( Trichoplusia ni ) in the present invention. Said regulatory polynucleotide sequences promote stronger foreign gene expression in the baculovirus system than the conventional polyhedrin promoter. Additionally, the combination of the new larva-derived promoters of the invention with the pL promoter increased baculovirus expression levels up to 61%-375% (depending on the time of infection) with respect to conventional baculo viruses used in the biotechnology industry. Promoter pB2 also drives gene expression at earlier times than polyhedrin promoter, being this feature a great advantage for correct protein folding and posttranslational modification. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2626590-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2766887-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2674438-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2619161-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014086981-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982239-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102286534-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102286534-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701983-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012168492-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879280-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012168493-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012168788-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012168789-A3 |
priorityDate |
2008-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |