http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010024704-A4
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00eb1f8edaa4f98bc93972b04ef98865 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692d7527fecd287eb46cb744adf1a62b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f09677640672700d74850832c4d67a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13f3ad59e7a10b4fdfb2ad08d981b789 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-461 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate | 2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_553587911ef1adf57a5abd0096a89404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a746dfeea9a05b46cd51b838d03f0334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b606f24de664cfdb6f8e4abdf7a3fa70 |
| publicationDate | 2010-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010024704-A4 |
| titleOfInvention | A gammacarboxyglutamate-rich protein, methods and assays for its detection, purification and quantification and uses thereof |
| abstract | The present invention refers to a gammacarboxyglutamate -rich protein that shows in vivo a high capacity to bind calcium through specific gamma carboxylated glutamic acid residues (Gla). It includes a description of the referred protein, purification procedures, protein detection and quantification tools and methods.. This invention also refers to a kit for the detection and quantification of said protein in samples. This kit includes the use of one or more antibodies produced against the homologous sequence of the target species to be analyzed, and thus, methods for the production of such antibodies are disclosed as well. In another aspect of the invention, the methods and tools described hereby are used as biomarkers for evaluation of presence or risk to develop certain diseases. In another aspect of this invention, available complete GRP cDNA and gene sequences obtained from several species also enable the in vitro production of antigens, the quantification of GRP expression, the screening of GRP polymorphisms to access the predisposition for certain diseases and the screening for GRP mutations. |
| priorityDate | 2008-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.