| abstract |
The present invention relates to a sustained release tablet containing talniflumate. More specifically, the present invention relates to a talniflumate sustained release tablet formed as a drug coated tablet comprising a cored tablet and a double layered tablet or a drug coating layer. A solubilizing aid is used to increase the solubility of talniflumate which is an insoluble drug in the tablet. The tablet contains hydrophilic polymers to stablize the sustained release in the user’s body. The sustained release tablet containing talniflumate according to the present invention has a relatively easy manufacturing process and is able to control release rate. Also, the tablet has excellent release efficiency for gradually releasing drug components in the body at a constant rate, compared with conventional immediate release talniflumate 370, 720 mg formulations which are available. Therefore, the tablet has an advantage that the inconvenience of administering three times a day is relieved by administering once or twice a day. |