abstract |
A method for treatment of adverse biological conditions is provided, wherein a biologically active agent such as a macromolecular biomolecule, e.g., a nucleic acid or a peptidic compound, is administered to a subject in need of such treatment in a formulation containing a transport enhancer having the structure of formula (I) wherein Q, R 1 , and R 2 are as defined herein. Methylsulfonylmethane (MSM) is a representative and preferred transport enhancer. Formulations are also provided. |