| abstract |
The invention is directed to a frozen pharmaceutical formulation suitable for administration to a subject parenterally, comprising a therapeutically effective amount of tigecycline and an agent selected from the group consisting of lactose, dextrose, glucose, mannose, sucrose, ribose, xylose and a combination thereof, wherein the formulation in a pre-frozen state at about 22 o C 4.0 to 5.5, and methods of making and kits comprising the same or in an unfrozen state at about 22 o C has a pH in the range of from. |