http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010017056-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ff3fb405e4d497fa0146ad93257f51c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1617 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 2009-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d2a7b8015b46860eb64ea1434e3932 |
| publicationDate | 2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2010017056-A1 |
| titleOfInvention | Orally administered solid formulations containing a hydrophobic drug and tpgs |
| abstract | A solid pharmaceutical formulation suitable for oral administration is described. The formulation is in the form of beads and contains a therapeutically effective amount of an hydrophobic active pharmaceutical ingredient (API), vitamin E TPGS, a filler/spheronization agent, a binder and a superdisintegrant. Processes for preparing the formulation are also described. One process involves wetting a dry mixture comprising the API, the filler/spheronization agent, the binder and the superdisintegrant with a solution of vitamin E TPGS in a granulation fluid (e.g., water optionally mixed with an alcohol), granulating the wetted mixture, extruding the resulting granulated mass, spheronizing the extrudate to provide beads, and drying the beads. Another process involves wet granulating a dry blend of API, spray-dried granules of vitamin E TPGS, filler/spheronization agent, binder and superdisintegrant, extruding the wet granulate, spheronizing the extrudate to beads, and drying the beads. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022072099-A1 |
| priorityDate | 2008-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.