| abstract |
A compound having the structure wherein X is selected from the group consisting of: a bond, -NHCH 2 (CH 2 ) n CH 2 OC(O), -CH 2 NHC(O)CH 2 NHC(O)-, -CH 2 OC(O), -OCH(CH 3 )OC(O)-, -OCH 2 OC(O)-, -O-, -NR 1 -, -CR 1 R 3 -, -(CH 2 ) P -, -(CH2) q NR 1 C(O)-, -CHR 5 NR 2 C(O)-, -(CH 2 ) q C(O)-, -(CH 2 ) q C(O)NR 1 -, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension. |