| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15c7c21ac1e53145e69eaf7909ba1d7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0dc3cde8b2594cd02a4a0a14d4434887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9ba304908c7187b486482f16a0f6158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_430a4ea48239cf576d087ccf281cf2a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39a40cef50d97e42b314421833b5a89e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 |
| filingDate |
2009-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdc5939d8414b31a5c9d616e104a91a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_221b83375f13d2b69e3e48fc70eb75be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a78901678f0c6c11d22e8c0a4223287
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_775bfc704dbca983c92f231f6df86fcc |
| publicationDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010013510-A1 |
| titleOfInvention |
Process for production of optically active compound |
| abstract |
A 2-aryl-2-halomethyl-4-chloromethyl-1,3-dioxolane (A) can be produced conveniently without decreasing its optical purity by reacting an optically active monochlorohydrin and an aryl (halomethyl) ketone (starting materials) with each other in the presence of an acid catalyst. From the optically active compound (A) thus produced, an optically active carboxylic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl) methyl ester and an optically active sulfonic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl) methyl ester (both of which are useful intermediates for the production of ketoconazole) can be produced with good efficiency. An optically active trans-carboxylic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl) methyl ester can be isomerized into its cis-form in the presence of an acid catalyst. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104260930-A |
| priorityDate |
2008-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |