| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9346661a91ad99852777f070fd2b6cdc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4e0fcf309b0d49f890b63cfe2018d4a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1836
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0043 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2009-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5452e76bbb8bc594a3ab0376cf9cd98f |
| publicationDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010012473-A2 |
| titleOfInvention |
Hydrolase-specific nanosensors, methods for producing them and uses in molecular imaging |
| abstract |
The present invention relates to hydrolase-specific sensor compounds which comprise a coated nanoparticle or core and a multimeric domain comprising a hydrolase-specific cleavage site. After cleavage by the hydrolase, the hydrolase-specific sensor compounds are transformed from a stable sensor compound to an aggregative compound, which allows in vivo detection and imaging of the aggregates. The present invention further relates to the uses of the hydrolase-specific sensor compounds as hydrolase reporter and as shuttles for therapeutic compounds, in particular as theranostics in magnetic thermotherapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8871189-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4088744-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011123030-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108690858-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015059482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110302400-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108690858-B |
| priorityDate |
2008-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |