abstract |
The present invention relates to the preparation and use of a glycolipid fraction from Oscillatoria Planktothrix sp. , for the treatment and/or prevention of bacterial gum diseases primarily caused by: Actinobacillum actinomycetemconcomitans , Porphyromonas gingivalis , Tannerella forsythia , Treponema denticola and even more preferably by Porphyromonas gingivalis . Said gum diseases, in particular gingivitis and periodontitis (pyorrhea), are primarily caused by a pro-inflammatory response to components of P. gingivalis , leading to destruction of periodontal tissue, and are often accompanied by osteoclastogenesis (increased number of osteoclasts responsible for destruction of bone tissue), and by chronic infection. |