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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a0711b262de5694d05f51c82d485899
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publicationDate 2010-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2010005067-A1
titleOfInvention Reagent for detecting type of allele based on polymorphism of siglec14 gene
abstract SIGLEC14 protein is expressed in some persons but is not expressed in some persons.  Persons in which SIGLEC14 protein is not expressed have a SIGLEC14/5 fusion gene.  SIGLEC14 gene has polymorphisms.nThus, disclosed is a reagent for detecting a polymorphism of SIGLEC14 gene, which comprises a primer pair capable of amplifying SIGLEC14 gene specifically, a probe capable of hybridizing with SIGLEC14 gene specifically or an antibody capable of recognizing specifically SIGLEC14 protein depicted in SEQ ID NO:4.  Also disclosed is a reagent for detecting an anti-SIGLEC14 antibody, which is characterized by comprising a protein having the amino acid sequence depicted in SEQ ID NO:4 or a cell capable of expressing a protein having the amino acid sequence depicted in SEQ ID NO:4.
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