| abstract |
The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the protein disulfide isomerase tumor marker in a biological sample from a patient suspected of being affected by colorectal cancer through the use of at least one anti-PDI monoclonal antibody against a PDI epitope selected from among the epitopes of sequence SEQ ID NO:1, SEQ ID NO:2 with a similar aromatic amino acid in the three-dimensional PDI structure, and SEQ ID NO:3, said method being useful in the early diagnosis, screening, therapeutic follow-up, prognosis, and relapse diagnosis in the field of colorectal cancer. |