Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0cea8e6cf771cf266bb2490a4e54dd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18c2ae4d1f35d366fe891f02af55e3fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87471dde7f69f8e5ad8a25bcd0d33789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5faadba6c0c1781186a9221b777cacd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08456fa3d4b752b3cedff05888fea340 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-78 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
filingDate |
2009-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a6ed16692947367a16a00c189544cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7822e5f62ddf43bb0b20775e655142ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44e3a886d398873d7616ba7f00aa9b67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ef3d8ab55710a46a091b9f7a46c7e64 |
publicationDate |
2010-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2010002636-A1 |
titleOfInvention |
Assays for nuclear hormone receptor binding |
abstract |
Methods and genetic constructs are provided for detecting the binding of nuclear hormone receptors to a coactivator/corepressor. The methods employ enzyme fragment complementation using fragments of β-galactosidase as the detection system. Cells are transformed to express the large fragment of β-galactosidase fused to a member of the complex with NHR for initiation of transcription and have it localized in the nucleus and to express the small fragment of β-galactosidase fused to the nuclear hormone receptor for binding to the member upon stimulation with a ligand. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3947714-A4 |
priorityDate |
2008-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |