| abstract |
The present invention relates to use of a matrix for the oral administration, in tablet form, of gradual continuous release Mg provided with a protective coating slowing down the gastric dissolution of the Mg, said matrix being characterized in that it includes, for the administration (A) of 90 to 110 parts by weight of magnesium, the following ingredients: (B1) 180 to 190 parts by weight of hydroxypropylmethyl cellulose; (B2) 19.8 to 22.2 parts by weight of glyceryl behenate; (C1) 10 to 12 parts by weight of lactose; and (C2) 10 to 12 parts by weight of colloidal silica. The invention also relates to the gradual release composition including said matrix and the coating thereof. |