abstract |
A compound having the structure (I) wherein R is an angiotensin II receptor antagonist selected from the group consisting of (IIa)- (IIh); A is (Formula) wherein R l and R 2 are independently selected from the group consisting of hydrogen and C 1-4 alkyl. Y is X 0 -Z wherein X 0 is selected from the group consisting of: -O-, -O-CO-, -OCOO-, -OCONH- and -OSO 2 -; Z is a nitric oxide releasing moiety, or a pharmaceutically acceptable salt thereof. |