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filingDate 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab6e885e8c6659436d5b538496a2b98b
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publicationDate 2009-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2009146312-A1
titleOfInvention Methods and apparatus for determining a central aortic pressure waveform from a peripheral artery pressure waveform
abstract A method is provided for determining a central aortic pressure (AP) waveform for a subject. The method includes measuring a peripheral artery pressure (PAP) waveform from the subject, employing a distributed model to define a pressure-to-pressure transfer function relating PAP to AP and a pressure-to-flow transfer function relating PAP to a central arterial flow in terms of the same unknown parameters, estimating the unknown parameters by finding the pressure-to-flow transfer function, which when applied to the measured PAP waveform, minimizes the magnitude of the central arterial flow waveform during diastole, and applying the pressure-to-pressure transfer function with the estimated parameters to determine an AP waveform for the subject.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011106245-A1
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