http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009143266-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4feb96637485b9ecb7a3145e6321e8f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d595ec481a2a081fed4aa2fd4ff52d8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-35 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
filingDate | 2009-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6e46c48a1ecf5fffd23a3b425af23dd |
publicationDate | 2009-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2009143266-A1 |
titleOfInvention | Targeting the efflux systems of mycobacterium tuberculosis |
abstract | Provided herein are methods of reducing drug resistance in Mycobacterium tuberculosis (Mtb). The methods comprise contacting the Mtb with an agent, wherein the agent inhibits the activity of an efflux complex. Also provided are methods of treating Mtb in a subject. The methods comprise administering to the subject an agent that inhibits the activity of an efflux complex; and administering to the subject a tuberculosis treating agent. Further provided is a method of screening for an agent that reduces drug resistance in Mtb. The methods comprise providing an Mtb with a mutant efflux complex; and contacting Mtb with an agent to be tested and a tuberculosis treating agent. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022269277-A1 |
priorityDate | 2008-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 530.