| abstract |
Compounds of Formula (I) or a pharmaceutically acceptable salt or N-oxide thereof; Formula (I) (relative stereochemistry shown) wherein: Z 1 , Z 2 , L are as defined, U represents a cyclic group selected from: phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl; m is 0 or 1, n is independently 0 or 1; and substituent(s) R 5 and R 6 are independently selected from: halo, CF 3 , OCF 3 , C 1_3 alkyl, C 1_3 alkoxy, nitro and cyano. Compounds of Formula (I) have anti -tuberculosis and antibacterial activity. |