| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03debc5d1c84fe68cccfc675f7b700db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70da7af5b2a07a23c44eaf4d39b69dcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d952fdcdfd48e3cb69628ebbb737887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea3551f32b5ff6aeff029d22a4cc0f8a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb77d5ac45171648df429eae034009b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_107c848e15e71c4abe969edd5baee688
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f48391725ce7f9364f983e51b14de1d8 |
| publicationDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009138794-A1 |
| titleOfInvention |
Imidazoquinazoline derivatives as anagrelide analogues for the treatment of myeloprolific diseases and thrombotic diseases |
| abstract |
This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103180323-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013541556-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011319706-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103180323-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012052781-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9067944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AP-3540-A |
| priorityDate |
2008-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |