| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a4254580bc57d5de92ce4453207289e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edf214d83c3f0f2bdc249e8079adf14d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b7411b46273ec9e4378da5721414cd2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-208
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2009-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94729068a0373c20512b66d8b084a80c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee00dae0ad1602a084505e6482c6418b |
| publicationDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2009138396-A2 |
| titleOfInvention |
Conjugates for the treatment of mesothelioma |
| abstract |
The present invention provides conjugates of cytokines and targeting peptides that is able to bind to a receptor expressed on tumor-associated vessels or to a component of the extracellular matrix associated to the tumor vessels, for treatment of malignant pleural mesothelioma. In particular, the invention provides conjugates comprising the cytokine TNF linked to a peptide containing the NGR motif. The invention further provides pharmaceutical compositions comprising such conjugate and pharmaceutical formulations comprising conjugates dissolved in appropriate buffers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014520510-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016175916-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018207115-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10202464-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10323098-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184009-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012045719-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11111312-B2 |
| priorityDate |
2008-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |